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Rigel to Presents at Upcoming Investors Conferences

South San Francisco, CA - June 10, 2005

Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) today announced that its management will present an update of the company’s clinical and other research and development activities at the following upcoming investor conferences:

    June 13, 2005, 1:30 p.m. Pacific Time: Thomas Weisel Partners Growth Forum 7.0 in San Francisco, CA. James M. Gower, Rigel’s chairman and chief executive officer, will be making the presentation; and

    June 21, 2005, 9:45 a.m. Eastern Time: BIO 2005 Business Forum at the Pennsylvania Convention Center (Room E) in Philadelphia, PA. Raul Rodriguez, the company’s executive vice president and chief operating officer, will be making the presentation (this presentation will not be webcast).

To access the live audio webcast or the subsequent archived recording, log on to www.rigel.com/rigel/events. Please connect to Rigel's website several minutes prior to the start of the live webcast to ensure adequate time for any software download that may be necessary.

About Rigel (www.rigel.com)
Rigel's mission is to become a source of novel, small-molecule drugs to address large, unmet medical needs. We have four research and development programs investigating treatments for asthma/allergy, rheumatoid arthritis, oncology and hepatitis C. Our strategy is to initiate clinical trials with at least one new product candidate annually and to pursue partnerships with pharmaceutical and biotechnology companies for late-stage clinical development and commercialization of those product candidates.

This press release contains "forward-looking" statements, including statements related to Rigel's plans to pursue clinical development of product candidates and the timing thereof and the potential efficacy of product candidates. Any statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Words such as "plans," "intends," "expects" and similar expressions are intended to identify these forward-looking statements. There are a number of important factors that could cause Rigel's results to differ materially from those indicated by these forward-looking statements, including risks associated with the timing and success of clinical trials and the commercialization of product candidates, as well as other risks detailed from time to time in Rigel's SEC reports, including its Annual Report on Form 10-K for the year ended December 31, 2004 and its Quarterly Report on Form 10-Q for the quarter ended March 31, 2005. Rigel does not undertake any obligation to update forward-looking statements.

Contact: Jim Welch
Phone: 650.624.1176
Email: invrel@rigel.com
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