Stock-based Compensation (Details) - USD ($) |
3 Months Ended | 9 Months Ended | ||
|---|---|---|---|---|
Sep. 30, 2016 |
Sep. 30, 2015 |
Sep. 30, 2016 |
Sep. 30, 2015 |
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| Stock-based compensation expense related to stock-based awards | ||||
| Total stock-based compensation expense | $ 1,714,000 | $ 1,815,000 | $ 5,166,000 | $ 5,778,000 |
| Research and development | ||||
| Stock-based compensation expense related to stock-based awards | ||||
| Total stock-based compensation expense | 643,000 | 966,000 | 2,746,000 | 3,182,000 |
| Incremental stock-based compensation expense | 641,000 | |||
| General and administrative | ||||
| Stock-based compensation expense related to stock-based awards | ||||
| Total stock-based compensation expense | 572,000 | $ 849,000 | 1,921,000 | $ 2,596,000 |
| Restructuring charge | ||||
| Stock-based compensation expense related to stock-based awards | ||||
| Total stock-based compensation expense | $ 499,000 | $ 499,000 | ||
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- Definition Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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- Definition An excess of the fair value of the modified award over the fair value of the award immediately before the modification. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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