Quarterly report pursuant to Section 13 or 15(d)

CONDENSED STATEMENTS OF CASH FLOWS

v3.8.0.1
CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Operating activities    
Net loss $ (52,121,000) $ (53,626,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 2,928,000 4,667,000
Gain on disposal of assets (732,000)  
Loss on sublease 495,000  
Depreciation and amortization 352,000 798,000
Non-cash restructuring charges   818,000
Net amortization of premium on short-term investment (198,000)  
Changes in assets and liabilities:    
Accounts receivable   203,000
Prepaid and other current assets 16,000 1,253,000
Other assets 96,000 130,000
Accounts payable (3,390,000) (1,245,000)
Accrued compensation 658,000 (1,699,000)
Accrued research and development (1,473,000) 2,733,000
Other accrued liabilities 447,000 (92,000)
Deferred revenue   (13,427,000)
Deferred rent and other long term liabilities (4,920,000) (3,938,000)
Net cash used in operating activities (57,842,000) (63,425,000)
Investing activities    
Purchases of short-term investments (64,235,000) (82,523,000)
Maturities of short-term investments 79,381,000 106,091,000
Proceeds from disposal of assets 732,000  
Capital expenditures (111,000) (798,000)
Net cash provided by investing activities 15,767,000 22,770,000
Financing activities    
Net proceeds from issuances of common stock upon exercise of options and participation in employee stock purchase plan 1,580,000 932,000
Proceeds from sale and issuance of common stock, net of offering costs 48,742,000 22,217,000
Net cash provided by financing activities 50,322,000 23,149,000
Net increase (decrease) in cash and cash equivalents 8,247,000 (17,506,000)
Cash and cash equivalents at beginning of period 17,632,000 43,456,000
Cash and cash equivalents at end of period $ 25,879,000 $ 25,950,000