Annual report pursuant to Section 13 and 15(d)

STATEMENTS OF OPERATIONS

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STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
STATEMENTS OF OPERATIONS      
Contract revenues from collaborations $ 7,150 $ 2,250 $ 4,750
Costs and expenses:      
Research and development 75,328 78,778 69,350
General and administrative 19,612 22,849 21,768
Restructuring charges 1,679    
Total costs and expenses 96,619 101,627 91,118
Loss from operations (89,469) (99,377) (86,368)
Interest income 442 537 420
Interest expense     (25)
Net loss $ (89,027) $ (98,840) $ (85,973)
Net loss per share, basic and diluted (in dollars per share) $ (1.02) $ (1.32) $ (1.36)
Weighted average shares used in computing net loss per share, basic and diluted (in shares) 87,288 74,967 63,329