Quarterly report pursuant to Section 13 or 15(d)

Sponsored Research and License Agreements (Details)

v3.19.1
Sponsored Research and License Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended
Jan. 31, 2019
Oct. 31, 2018
Mar. 31, 2019
Dec. 31, 2018
Kissei        
Collaborations        
Upfront payment received   $ 33,000,000    
Contingent payments   $ 147,000,000    
Revenue recognized       $ 30,600,000
Grifols        
Collaborations        
Upfront payment received $ 30,000,000   $ 5,000,000  
Deferred revenue related to upfront payment     25,500,000  
Revenue recognized     4,400,000  
Grifols | Research Services        
Collaborations        
Revenue recognized     71,000  
Grifols | Commercial Milestones        
Collaborations        
Contingent payments 297,500,000      
fostamatinib | Kissei        
Collaborations        
Deferred revenue related to upfront payment     2,400,000  
Revenue recognized     $ 27,000  
fostamatinib | Grifols | Prior written notice following the second anniversary of the first MAA approval of fostamatinib in Europe and Turkey        
Collaborations        
Right to terminate agreement within number of months after second anniversary     6 months  
fostamatinib | Grifols | Terminated agreement upon prior written notice within six months after second anniversary of agreement        
Collaborations        
Contingent upfront fee, refund requirement 25,000,000      
fostamatinib | Grifols | EMA approval of fostamatinib for treatment of chronic ITP        
Collaborations        
Contingent payments $ 20,000,000      
fostamatinib | Grifols | Maximum        
Collaborations        
Royalty payment as a percentage of net sales 30.00%