Quarterly report pursuant to Section 13 or 15(d)

SPONSORED RESEARCH AND LICENSE AGREEMENTS AND GOVERNMENT CONTRACT (Details)

v3.22.1
SPONSORED RESEARCH AND LICENSE AGREEMENTS AND GOVERNMENT CONTRACT (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended 15 Months Ended
Feb. 28, 2021
Jan. 31, 2021
Feb. 29, 2020
Dec. 31, 2019
Oct. 31, 2019
Jan. 31, 2019
Oct. 31, 2018
Mar. 31, 2022
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Mar. 31, 2022
Dec. 31, 2021
Collaborations                          
Upfront payment received               $ 125,000,000.0          
Accretion expense               700,000 $ 100,000        
Payment of cost share to collaboration partner               2,118,000          
Accounts receivable               15,240,000       $ 15,240,000 $ 15,472,000
License agreement with unrelated third party                          
Collaborations                          
Revenue recognized                 4,000,000        
Proceeds from License Fees Received $ 4,000,000.0                        
One-time fee received from license rights granted $ 4,000,000.0                        
Specified Development Events [Member]                          
Collaborations                          
Contingent payments               279,500,000          
Specified Regulatory Events [Member]                          
Collaborations                          
Contingent payments               285,600,000          
Specified Product Launch Events [Member]                          
Collaborations                          
Contingent payments               778,500,000          
Development and regulatory milestones by non-CNS disease products                          
Collaborations                          
Contingent payments               330,000,000.0          
Development and regulatory milestones by non-CNS disease products | Milestone payments on a product-by-product basis                          
Collaborations                          
Contingent payments               100,000,000.0          
Development and regulatory milestones by CNS disease products                          
Collaborations                          
Contingent payments               255,000,000.0          
Development and regulatory milestones by CNS disease products | Milestone payments on a product-by-product basis                          
Collaborations                          
Contingent payments               150,000,000.0          
Maximum                          
Collaborations                          
Contingent payments               1,300,000,000          
Grifols                          
Collaborations                          
Contingent payments               277,500,000          
Upfront payment received           $ 30,000,000.0              
Revenue, remaining performance obligation                         5,000,000.0
Deferred revenue               400,000       400,000 700,000
Revenue, cumulative catch-up                   $ 25,000,000.0      
Grifols | Commercial Milestones                          
Collaborations                          
Contingent payments           $ 297,500,000              
Revenue recognized               1,000,000.0 1,000,000.0        
Grifols | Upon EMA approval of fostamatinib for treatment of chronic ITP                          
Collaborations                          
Revenue, cumulative catch-up                   $ 20,000,000.0      
Kissei                          
Collaborations                          
Contingent payments             $ 147,000,000.0            
Upfront payment received             $ 33,000,000.0            
Revenue, remaining performance obligation               33,000,000.0       33,000,000.0  
Deferred revenue               1,400,000       1,400,000 1,400,000
fostamatinib                          
Collaborations                          
Revenue recognized               0 3,000,000.0     10,500,000  
Government contract   $ 16,500,000                      
Remaining amount of government award expected to be received in succeeding periods               6,000,000.0          
fostamatinib | Grifols                          
Collaborations                          
Collaborative payment received     $ 20,000,000.0                    
Markup percentage       30.00%                  
fostamatinib | Grifols | Upon EMA approval of fostamatinib for treatment of chronic ITP                          
Collaborations                          
Contingent payments     17,500,000                    
fostamatinib | Grifols | Creditable advance royalty payment                          
Collaborations                          
Collaborative payment received     $ 2,500,000                    
fostamatinib | Grifols | Maximum                          
Collaborations                          
Royalty payment as a percentage of net sales                     30.00%    
fostamatinib | Medison Pharma | Financing arrangement                          
Collaborations                          
Upfront payment received         $ 5,000,000.0                
Financing liability with accreted interest expense               $ 5,600,000       5,600,000 5,600,000
fostamatinib | Medison Pharma | Commercial and license agreements                          
Collaborations                          
Upfront payment received         $ 5,000,000.0                
R552                          
Collaborations                          
Company's percentage of development costs               20.00%          
Financing component liability               $ 57,900,000       57,900,000  
Financing liability interest accretion discount rate               6.40%          
Financing liability with accreted interest expense               $ 59,200,000       59,200,000 $ 60,700,000
Development costs due to collaboration partner               4,900,000       4,900,000  
Payment of cost share to collaboration partner               2,100,000          
Revenue, remaining performance obligation               67,100,000       67,100,000  
R552 | Maximum                          
Collaborations                          
Funding commitment               65,000,000.0       65,000,000.0  
Non-CNS penetrant IP                          
Collaborations                          
Revenue recognized                 60,400,000        
Non-CNS penetrant IP | Licensed Rights                          
Collaborations                          
Revenue, remaining performance obligation                 6,700,000        
CNS penetrant IP                          
Collaborations                          
Revenue recognized               200,000 200,000        
Deferred revenue               300,000       $ 300,000  
Research and development services | Grifols                          
Collaborations                          
Revenue recognized               $ 300,000 $ 0