Quarterly report [Sections 13 or 15(d)]

Sponsored Research and License Agreements (Details)

v3.26.3
Sponsored Research and License Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 34 Months Ended
Jan. 31, 2024
Dec. 31, 2023
Apr. 30, 2021
Sep. 30, 2026
Jun. 30, 2026
Sep. 30, 2025
Jun. 30, 2025
Mar. 31, 2025
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Dec. 31, 2025
Collaborations                        
Upfront payment received     $ 125,000,000.0                  
Revenue recognized       $ 80,890,000   $ 69,462,000     $ 218,411,000 $ 224,480,000    
ocadusertib                        
Collaborations                        
Company's percentage of development costs                 20.00%      
Revenue recognized             $ 40,000,000.0          
Grifols                        
Collaborations                        
Deferred revenue       0         $ 0   $ 0 $ 0
Grifols | Royalty                        
Collaborations                        
Revenue recognized       2,500,000   1,900,000     6,200,000 5,000,000.0    
Kissei                        
Collaborations                        
Deferred revenue       0         0   0 0
Revenue recognized       3,200,000   1,800,000     6,700,000 3,900,000    
Kissei | fostamatinib                        
Collaborations                        
Deferred revenue       1,400,000         1,400,000   1,400,000 1,400,000
Revenue recognized         $ 4,200,000     $ 3,000,000.0        
Sublicensing fee payable         $ 1,000,000.0              
Medison | fostamatinib                        
Collaborations                        
Deferred revenue       0         0   0 $ 0
Revenue recognized       300,000   200,000     900,000 800,000    
Non-Central Nervous System, Specified Development And Regulatory Milestone                        
Collaborations                        
Contingent payments                 330,000,000.0      
Product-by-product Sales Milestone                        
Collaborations                        
Contingent payments                 100,000,000.0      
Central Nervous System, Specified Development And Regulatory Milestone                        
Collaborations                        
Contingent payments                 256,000,000.0      
Central Nervous System, Product-by-product Sales Milestone                        
Collaborations                        
Contingent payments                 150,000,000.0      
Delivery of drug supply for commercialization | Grifols                        
Collaborations                        
Revenue recognized       $ 1,200,000   $ 1,200,000     4,300,000 $ 4,900,000    
Collaborative Arrangement                        
Collaborations                        
Contingent payments                 652,100,000      
Collaborative Arrangement | Specified Development Events                        
Collaborations                        
Contingent payments                 190,100,000      
Collaborative Arrangement | Specified Product Launch Events                        
Collaborations                        
Contingent payments                 $ 462,000,000.0      
Strategic collaboration agreement with MDACC | REZLIDHIA                        
Collaborations                        
Amount due to collaboration partner   $ 15,000,000.0                    
Collaboration period   5 years                    
Payment of cost share to collaboration partner                     $ 5,300,000  
Strategic collaboration agreement with Mdacc, clinical study enrollment support | REZLIDHIA                        
Collaborations                        
Amount due to collaboration partner   $ 1,000,000.0                    
Strategic collaboration agreement with CONNECT | REZLIDHIA                        
Collaborations                        
Amount due to collaboration partner $ 3,000,000.0                      
Collaboration period 4 years