Annual report pursuant to Section 13 and 15(d)

STATEMENTS OF STOCKHOLDERS' EQUITY

v3.7.0.1
STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Balance at Dec. 31, 2013 $ 88 $ 1,057,390 $ 47 $ (849,274) $ 208,251
Balance (in shares) at Dec. 31, 2013 87,524,349        
Increase (Decrease) in Stockholders' Equity          
Net loss       (90,908) (90,908)
Net change in unrealized loss (gain) on short-term investments     (54)   (54)
Issuance of common stock upon exercise of options and participation in Purchase Plan   1,170     1,170
Issuance of common stock upon exercise of options and participation in Purchase Plan (in shares) 517,096        
Stock compensation expense   9,787     9,787
Balance at Dec. 31, 2014 $ 88 1,068,347 (7) (940,182) 128,246
Balance (in shares) at Dec. 31, 2014 88,041,445        
Increase (Decrease) in Stockholders' Equity          
Net loss       (51,464) (51,464)
Net change in unrealized loss (gain) on short-term investments     (37)   (37)
Issuance of common stock upon exercise of options and participation in Purchase Plan $ 1 1,760     1,761
Issuance of common stock upon exercise of options and participation in Purchase Plan (in shares) 790,832        
Issuance of common stock, net of offering costs $ 2 5,470     5,472
Issuance of common stock, net of offering costs (in shares) 1,722,312        
Stock compensation expense   7,403     7,403
Balance at Dec. 31, 2015 $ 91 1,082,980 (44) (991,646) 91,381
Balance (in shares) at Dec. 31, 2015 90,554,589        
Increase (Decrease) in Stockholders' Equity          
Net loss       (69,216) (69,216)
Net change in unrealized loss (gain) on short-term investments     26   26
Issuance of common stock upon exercise of options and participation in Purchase Plan $ 1 1,597     1,598
Issuance of common stock upon exercise of options and participation in Purchase Plan (in shares) 819,266        
Issuance of common stock, net of offering costs $ 8 23,398     23,406
Issuance of common stock, net of offering costs (in shares) 7,895,563        
Stock compensation expense   7,832     7,832
Balance at Dec. 31, 2016 $ 100 $ 1,115,807 $ (18) $ (1,060,862) $ 55,027
Balance (in shares) at Dec. 31, 2016 99,269,418