Quarterly report pursuant to Section 13 or 15(d)

Sponsored Research and License Agreements (Details)

v3.5.0.2
Sponsored Research and License Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Jun. 30, 2016
Sep. 30, 2015
Aug. 31, 2015
Mar. 31, 2015
Jun. 30, 2016
Sep. 30, 2015
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Feb. 28, 2015
Collaborative Arrangement                    
Collaborations                    
Maximum amount of contingent payments receivable $ 531,900,000       $ 531,900,000     $ 531,900,000    
Specified Development Events | Collaborative Arrangement                    
Collaborations                    
Maximum amount of contingent payments receivable 148,800,000       148,800,000     148,800,000    
Specified Regulatory Events | Collaborative Arrangement                    
Collaborations                    
Maximum amount of contingent payments receivable 345,600,000       345,600,000     345,600,000    
Specified Product Launch Events | Collaborative Arrangement                    
Collaborations                    
Maximum amount of contingent payments receivable 37,500,000       37,500,000     37,500,000    
Bristol-Myers Squibb Company                    
Collaborations                    
Noncreditable and nonrefundable upfront payment by BMS       $ 30,000,000            
Deferred revenue related to upfront payment 3,800,000       3,800,000     3,800,000   $ 30,000,000
Revenue recognized         4,800,000   $ 4,800,000 9,700,000 $ 6,900,000  
Bristol-Myers Squibb Company | Research Activities                    
Collaborations                    
Revenue recognized         95,000   $ 350,000 290,000 $ 456,000  
Bristol-Myers Squibb Company | Minimum                    
Collaborations                    
Contingent payments               $ 309,000,000    
Aclaris                    
Collaborations                    
Upfront fee received   $ 8,000,000                
Contingent payments     $ 80,000,000              
Revenue recognized           $ 8,000,000        
Ber Gen Bio A S [Member]                    
Collaborations                    
Upfront fee received 1,700,000                  
Revenue recognized         $ 3,700,000          
Payment received from exercise of option rights $ 2,000,000