Adult Chronic Immune Thrombocytopenia (ITP)
Target: Spleen tyrosine kinase (SYK)
Pre-Clinical | Phase 1 | Phase 2 | Phase 3 | Approved |
---|---|---|---|---|
Pre-Clinical
Complete
|
Phase 1
Complete
|
Phase 2
Complete
|
Phase 3
Complete
|
Approved
Complete
|
R/R Acute Myeloid Leukemia
Target: Mutant isocitrate dehydrogenase–1 (mIDH1)
Pre-clinical | Phase 1 | Phase 2 | NDA FILED | Approved |
---|---|---|---|---|
Pre-clinical
Complete
|
Phase 1
Complete
|
Phase 2
Complete
|
NDA FILED
Complete
|
Approved
Complete
|
Liposarcoma
Target: Murine double minute 2 (MDM2)
Pre-clinical | Phase 1 | Phase 2 | Phase 3 | Approved |
---|---|---|---|---|
Pre-clinical
Complete
|
Phase 1
Complete
|
Phase 2
Complete
|
Phase 3
Complete
|
Approved
Not Started
|
NSCLC & COVID-19
Target: AXL receptor tyrosine kinase (AXL)
Pre-clinical | Phase 1 | Phase 2 | Phase 3 | Approved |
---|---|---|---|---|
Pre-clinical
Complete
|
Phase 1
Complete
|
Phase 2
In Progress
|
Phase 3
Not Started
|
Approved
Not Started
|
Rheumatoid Arthritis
Target: Receptor-interacting serine/threonine-protein kinase 1 (RIPK1)
Pre-clinical | Phase 1 | Phase 2 | Phase 3 | Approved |
---|---|---|---|---|
Pre-clinical
Complete
|
Phase 1
Complete
|
Phase 2
In Progress
|
Phase 3
Not Started
|
Approved
Not Started
|
CNS Diseases
Target: Receptor-interacting serine/threonine-protein kinase 1 (RIPK1)
Pre-clinical | Phase 1 | Phase 2 | Phase 3 | Approved |
---|---|---|---|---|
Pre-clinical
In Progress
|
Phase 1
Not Started
|
Phase 2
Not Started
|
Phase 3
Not Started
|
Approved
Not Started
|
1 Please see the TAVALISSE Full Prescribing Information
2 Please see the REZLIDHIA Full Prescribing Information, including Boxed WARNING
* Investigational compounds in these indications have not been submitted for FDA review