In January 2020, Rigel received approval of its marketing authorization application (MAA) for fostamatinib for the treatment of chronic immune thrombocytopenia in adult patients who are refractory to other treatments. The product launched in July 2020 and is marketed in Europe under the brand name TAVLESSE® (fostamatinib). It is the first and only spleen tyrosine kinase (SYK) inhibitor approved in Europe for this indication.

In November 2020, Grifols exercised its option to expand its territory to include the Middle East, North Africa, Russia and CIS.

Rigel received an upfront cash payment, and is eligible for regulatory and commercial milestone payments, as well as tiered royalty payments on any future net sales of any products emerging from the collaboration.