In November 2020, Rigel received approval from Health Canada for its new drug submission (NDS) for fostamatinib for the treatment of thrombocytopenia in adult patients with chronic immune thrombocytopenia (ITP) who have had an insufficient response to other treatments. The product is marketed in Canada under the brand name TAVALISSE® and it is the first and only spleen tyrosine kinase (SYK) inhibitor approved in Canada for this indication.
Rigel received an upfront payment of $5 million, which includes an advanced royalty payment, with the potential for approximately $35 million in regulatory and commercial milestones. In addition, the company will receive royalty payments beginning at 30% of net sales after credit for the advanced royalty payment is fulfilled.
Development of fostamatinib in Israel: